The licence for a custom-made medicinal product is an adaptive licence
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چکیده
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The purpose of this thesis is to develop Bayesian methodology together with the proper computational tools to address two different problems. The first problem which is more general from a methodological point of view appears in computer experiments. We consider emulation of realizations of a monotone function at a finite set of inputs available from a computationally intensive simulator. We de...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2014
ISSN: 0306-5251
DOI: 10.1111/bcp.12249